(Carbapenemase-producing Enterobacterales)
CPE represent one of the greatest challenges for the safe provision of healthcare and infection control in hospitals. High-risk patients require preemptive isolation until their carrier status can be confirmed. However, traditional culture-based methods require up to 72 hours for a result, placing increased pressure on bed availability and patient flow throughout the hospital.
On-demand PCR with the GeneXpert® system greatly improves time to result, allowing healthcare professionals to quickly identify, isolate and appropriately manage patients, helping prevent the spread and improve overall patient flow. That’s the PCRplus advantage.
Impact of Different CPE Screening Strategies in a Hospital Setting1
Reduction in time to identification of CPE positive patients
<4 Hours
On-demand PCR pathway
3 Days
Traditional testing pathway
Reduction in lost bed days due to CPE (50% in first 9 months alone)
108 Beds
On-demand PCR pathway
228 Beds
Traditional testing pathway
Reduction in the laboratory screening process steps
27 Steps
On-demand PCR pathway
110 Steps
Traditional testing pathway
Despite higher initial laboratory PCR costs, savings were made elsewhere through expediting test results, as well as improving the patient’s experience.
1 Corless C, et al. Impact of different carbapenemase-producing Enterobacterales screening strategies in a hospital setting. IPIP. 2020 May;3(2):100011.
© 2022-2023 Cepheid.