CPE

(Carbapenemase-producing Enterobacterales)

CPE represent one of the greatest challenges for the safe provision of healthcare and infection control in hospitals. High-risk patients require preemptive isolation until their carrier status can be confirmed. However, traditional culture-based methods require up to 72 hours for a result, placing increased pressure on bed availability and patient flow throughout the hospital.

Fast & Accurate PCR for Improved Patient Pathways

On-demand PCR with the GeneXpert® system greatly improves time to result, allowing healthcare professionals to quickly identify, isolate and appropriately manage patients, helping prevent the spread and improve overall patient flow. That’s the PCRplus advantage.

Impact Case Study

Impact of Different CPE Screening Strategies in a Hospital Setting1

Reduction in time to identification of CPE positive patients

<4 Hours

On-demand PCR pathway

3 Days

Traditional testing pathway

Reduction in lost bed days due to CPE (50% in first 9 months alone)

108 Beds

On-demand PCR pathway

228 Beds

Traditional testing pathway

Reduction in the laboratory screening process steps

27 Steps

On-demand PCR pathway

110 Steps

Traditional testing pathway

Despite higher initial laboratory PCR costs, savings were made elsewhere through expediting test results, as well as improving the patient’s experience.

Learn More

Corless C, et al. Impact of different carbapenemase-producing Enterobacterales screening strategies in a hospital setting. IPIP. 2020 May;3(2):100011.

 

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